-
Product name:
Varnex
-
Generic name:
Varenicline
-
Dosage form:
Oral tablets
-
Packaging:
Box of 3 blisters of scored 10 F.C. tablets
-
Drug Category:
Neurology and Psychiatry
Indications:
Varenicline is a nicotinic receptor partial agonist indicated for use as an aid to smoking cessation treatment
Dosage and Administration:
Begin varenicline dosing one week before the date set by the patient to stop smoking. Alternatively, the patient can begin varenicline dosing and then quit smoking between days 8 and 35 of treatment.
Starting week: 0.5 mg once daily on days 1–3 and 0.5 mg twice daily on days 4–7.
Continuing weeks: 1 mg twice daily for a total of 12 weeks.
An additional 12 weeks of treatment is recommended for successful quitters to increase likelihood of long-term abstinence.
Renal impairment: Reduce the dose in patients with severe renal impairment (estimated creatinine clearance <30 mL/min).
Consider dose reduction for patients who cannot tolerate adverse effects.
Another attempt at treatment is recommended for those who fail to stop smoking or relapse when factors contributing to the failed attempt have been addressed.
Provide patients with appropriate educational materials and counseling to support the quit attempt.
Contraindication:
Hypersensitivity to the active substance or to any of the excipients.
